Caliber Biotherapeutics, LLC is a biotechnology company based in Bryan, Texas with a mission to develop and commercialize protein-based therapeutics that improve outcomes for patients with cancer and other diseases. The Company utilizes technological innovations in biological research, product development, and manufacturing to create treatments with increased safety and effectiveness, while reducing both costs and development time.
Caliber has created a highly attractive pipeline of cancer therapeutics using the monoclonal antibody-interferon fusion protein technology through a joint venture with ImmunGene, Inc. (Thousand Oaks, CA). The joint venture, launched as Valor Biotherapeutics (www.valorbio.com), will develop three cancer fusion proteins targeting non-Hodgkin’s lymphoma, multiple myeloma, and breast cancers.
Caliber has also created a pipeline of biobetter products applying its expertise in the Nicotiana benthamiana plant-based expression and manufacturing of recombinant proteins. Caliber operates the world’s largest N. benthamiana expression based protein manufacturing facility in College Station, Texas. Under a DARPA challenge, the company has demonstrated the ability to rapidly produce substantial quantities of influenza vaccine antigen using this facility. Caliber’s technologies are being supported by the Cancer Prevention and Research Institution of Texas (CPRIT), DARPA, and several Texas based life sciences investors.